Kourosh Saeb-Parsy

Dr Kourosh Saeb-Parsy serves as a University Reader in the Department of Surgery at the University of Cambridge and holds an Honorary Transplant Consultant position. His research focuses on cellular and humoral immune responses in organ transplantation, with emphasis on improving graft survival through regenerative medicine and immunomodulation strategies. He is actively affiliated with the Anne McLaren Laboratory for Regenerative Medicine and the NIHR Blood and Transplant Research Unit.

His research spans Transplantation Immunology, Organ Preservation, and Cellular Therapy Development, utilizing advanced multi-omics and single-cell technologies. Key interests include cholangiocyte organoid therapies for biliary diseases, CAR-Treg applications in transplantation, and immune monitoring during organ storage. His work bridges laboratory discoveries with clinical translation to address critical challenges in transplant medicine.

Analysis of recent publications reveals strong emphasis on multi-omics integration for understanding cellular responses during organ preservation, immune regulation in transplantation, and organoid-based therapeutic development. His group pioneers techniques in spatial transcriptomics and mutagenesis analysis to characterize tissue niches and immune dynamics in transplant recipients.

Dr Saeb-Parsy contributes to the Department of Surgery's postgraduate research programs and collaborates extensively through the NIHR Blood and Transplant Research Unit. His laboratory operates within the Cambridge Regenerative Medicine ecosystem, focusing on translating mechanistic insights into clinical applications for improving transplant outcomes and developing novel cellular therapies.