Eric Bindels

Dr. Eric Bindels is a Researcher at the Hematology department of Erasmus MC. His work focuses on molecular mechanisms underlying hematological disorders, stem cell biology, and immune interactions in regenerative medicine. He leads projects exploring genetic drivers of leukemia, GATA2 deficiency syndromes, and kidney organoid immunology. His research integrates single-cell transcriptomics and genomics to study diseases like cystic fibrosis, myelodysplastic syndromes, and organ transplant immunology.

Major research areas include: 1) Leukemia oncogenesis and therapy resistance, 2) Genetic/epigenetic dysregulation in hematopoietic disorders, 3) Immune system interactions with organoids and transplanted tissues, 4) Forensic applications of single-cell DNA sequencing. His 78+ peer-reviewed articles span high-impact journals like Blood Advances, Nature Communications, and Cell Stem Cell.

Notable contributions include identifying somatic events in GATA2 deficiency, discovering EVI1-driven leukemia mechanisms, and demonstrating kidney organoid functionality in nephrology research. His work bridges basic science with clinical applications in transplantation medicine and precision oncology.