معرفی
Kelly McCall is a Professor in the Department of Biomedical Engineering at Ohio University's Russ College of Engineering and Technology. Her research focuses on inflammatory pathways in metabolic disorders, viral pathogenesis, and cancer biology, with specific expertise in diabetes, autoimmune diseases, and tumor immunology. She investigates molecular mechanisms of disease and develops novel therapeutic strategies using small-molecule inhibitors targeting key signaling pathways.
Dr. McCall's research examines the interplay between innate immunity and disease pathogenesis across multiple conditions. Her work explores TLR signaling in viral acceleration of type 1 diabetes, GSK-3 inhibition in COVID-19 and NAFLD, and cytokine modulation in cancer microenvironments. She employs diverse models including mouse genetics, cell cultures, and molecular techniques to dissect disease mechanisms.
Her publications demonstrate consistent focus on translational research with therapeutic applications. Recent work identifies novel inhibitors targeting GSK-3 and inflammatory pathways, while earlier research established phenylmethimazole derivatives as anti-inflammatory agents. This research continuum reflects her commitment to bridging basic science discoveries with clinical applications.
