معرفی
Katharina Hoerth is a researcher at the Medical Faculty Mannheim of Heidelberg University, leading studies on translation control mechanisms and phase transitions in cellular stress responses. Her work bridges cell cycle regulation, protein synthesis, and viral interactions, focusing on how CDK1 kinase activity integrates with ribosome biogenesis and stress granule dynamics. She investigates molecular adaptations enabling cells to survive damage and infection, particularly through liquid-liquid phase separation phenomena.
Research interests include the interplay between protein synthesis pathways and cellular proliferation, mechanisms governing replication stress responses, and how stress granules modulate antiviral defenses. Her team explores TIAR protein functions in nuclear granules and CDK1 regulation under DNA damage.
Publications highlight contributions to understanding flavivirus pathogenesis and the role of stress granules in viral infection contexts. Collaborations involve virology, cell biology, and biochemistry disciplines. Lab members and alumni contribute to ongoing projects at the interface of molecular stress responses and cellular homeostasis.
