معرفی
Dr. Barsanjit Mazumder is a Professor at Cleveland State University, affiliated with the Center for Gene Regulation in Health and Disease (GRHD) and the Department of Biological, Geological and Environmental Sciences within the College of Arts and Sciences. His research focuses on molecular mechanisms of gene regulation with particular emphasis on inflammation control and translational regulation in immune cells.
Dr. Mazumder's research interests center on endogenous cellular mechanisms to control inflammation, specifically studying how ribosomal proteins regulate translation during inflammatory responses. His laboratory discovered a unique translation regulation mechanism involving ribosomal protein L13a, which forms an RNA-binding complex that targets inflammatory chemokines. His work also explores ribosome biogenesis and viral gene expression mechanisms, with significant findings published in top journals including Cell, Molecular & Cellular Biology, and Journal of Immunology.
His publication record shows a consistent research trajectory over the past 15 years, with focus areas including the GAIT (Gamma-Activated Inhibitor of Translation) complex, ribosomal protein functions beyond protein synthesis, and post-transcriptional regulation of inflammatory responses. His work has important implications for understanding and treating inflammatory diseases such as atherosclerosis, ulcerative colitis, and endotoxemia.
Dr. Mazumder leads an active research laboratory with current students including PhD candidate Antara Roy and undergraduate researcher Danny Venorsky. His laboratory utilizes cellular and tissue-specific gene knockout mouse models to investigate translational control mechanisms in innate immune cells.
