معرفی
Kan Cao is a Professor and Associate Chair in the Molecular & Cellular Biology department at the University of Maryland. His research focuses on understanding premature aging disorders, particularly Hutchinson-Gilford Progeria Syndrome (HGPS), cellular senescence, telomere biology, and alternative splicing mechanisms. He holds a Ph.D. from Johns Hopkins University (2005).
Research Interests:
- Hutchinson-Gilford Progeria Syndrome
- Cellular Senescence and Aging Mechanisms
- Vascular Dysfunction in Progeria
- Genetic Therapies (e.g., base editing, antisense oligonucleotides)
- Anti-aging drug development (e.g., methylene blue)
- iPSC-derived disease modeling
Recent Work Trends: Recent studies emphasize therapeutic interventions for progeria using base editing, angiopoietin-2 modulation, and drug combinations (e.g., lonafarnib/everolimus). His team also explores aging-related transcriptomic shifts and vascular engineering models.
Grants/Labs:
- Co-founded Mblue Labs, a startup developing anti-aging skincare products.
- Collaborates with NIH and industry on progeria therapies. Recent grants include a $2M award for quantum biosensing in aging research (2024).
