Jürgen Moser

Dr. Jürgen Moser is a Senior Academic Councillor/Group Leader at the Institute of Microbiology, Technical University of Braunschweig, within the Faculty of Life Sciences. His group focuses on tetrapyrrole biosynthesis, bacterial lipid modification mechanisms, and microbial natural products. He holds a PhD in organic chemistry and has led research on antibiotic resistance, chlorophyll synthesis, and violacein production.

Education:

• 1991–1996: Studied Chemistry at Albert Ludwig University of Freiburg
• 1996–1997: Diploma thesis at Freiburg’s Department of Organic Chemistry (topic: phospholipase C structure)
• 1997–2000: PhD at Freiburg under Prof. D. Jahn (topic: glutamyl-tRNA reductase mechanism)

Research Interests:

• Enzymatic mechanisms of tetrapyrrole biosynthesis
• tRNA-dependent lipid modifications (e.g., alanyl- and lysyl-phosphatidylglycerol)
• Antibiotic resistance pathways in Pseudomonas aeruginosa and Acinetobacter baumannii
• Chlorophyll and bacteriochlorophyll synthesis in photosynthetic bacteria
• Biosynthesis of antimicrobial natural products like violacein

Publications: Recent work includes studies on carnitine degradation pathways in pathogens, lipid homeostasis in biofilms, and structural biology of nitrogenase-like enzymes. His research bridges microbiology, enzymology, and structural biology to uncover molecular mechanisms of bacterial adaptation and survival.

Lab/Team: The Moser Group investigates microbial metabolism and resistance mechanisms, with ongoing projects in the MINAS consortium for microbial natural products. Collaborations include structural biology (e.g., crystallography) and biophysical methods.