Jörg Scheuermann

Jörg Scheuermann is a Senior Lecturer and Principal Investigator at the ETH Zürich in the Department of Chemistry and Applied Biosciences. His research focuses on DNA-encoded chemical library (DEL) technology and its applications in drug discovery, including PROTAC development and small-molecule drug conjugates (SMDCs).

• Broad research areas: DEL technology, medicinal chemistry, bioconjugate chemistry

His work involves library construction, screening methodologies, hit validation, and translational applications against tumor-associated targets. Recent publications highlight innovations in dual-display DELs, tyrosinase inhibition, and ex vivo mass spectrometry analysis.

• Key contributions: Enzymatic DEL construction (SNF grant CRSII5_198673/1)
• 2020: Group leader at ETH Zürich
• Habilitation in DEL technology (2018)