معرفی
Dr. Julian Joseph Bosco is an Adjunct Senior Lecturer in the Faculty of Medicine at Monash University and holds clinical appointments at Alfred Health, Alfred Pathology, and Epworth Allergy Specialists. His expertise lies in Clinical Immunology, Allergy, and Immunopathology, with a focus on autoimmune diseases, immunodeficiency, and B-cell dysfunction.
Education:
- Bachelor of Medicine and Bachelor of Surgery with Honours, University of New South Wales (2002)
- PhD on immunoregulatory properties of CD52, Walter and Eliza Hall Institute of Medical Research
- Fellowship, Royal Australasian College of Physicians
- Fellowship, Royal College of Pathologists of Australasia
His research interests include:
- Inborn errors of immunity
- Immune responses in high-risk populations (e.g., post-splenectomy, immunocompromised)
- Autoantibody-associated autoimmune diseases
- Effects of biologic therapies on immune function
- SARS-CoV-2 immunity in immunodeficient patients
Recent publications highlight his work on B-cell immunology, vaccine responses after splenic injury, and complications of immunomodulatory drugs. His studies often involve translational research with clinical applications in immunodeficiency and allergic diseases.
Scientific Contributions:
- Active participation in major research projects including PROPHECY (immune responses to SARS-CoV-2)
- Development of assays for genetic variants in inborn errors of immunity
- Establishment of the Jeffrey Modell Center in Melbourne for primary immunodeficiency
Dr. Bosco serves as a Chief or Associate Investigator on multiple funded studies and collaborates with leading research institutes including Murdoch Children's Research Institute and Burnet Institute. He contributes to advancing clinical guidelines and public health strategies related to immune disorders.
Laboratory and Research Teams:
- Member of the Clinical Immunology and Allergy team at Alfred Hospital
- Collaborator in the van Zelm Laboratory (Monash University) focusing on B-cell development and immunodeficiency
- Part of multidisciplinary teams investigating post-traumatic immunity and vaccine efficacy
