معرفی
Joseph Puglisi is a Professor at the Department of Structural Biology, Stanford University School of Medicine, with over 25 years of leadership roles. He serves as Director of the Stanford Magnetic Resonance Laboratory and the International School of Biological Magnetic Resonance (Erice, Italy). His research focuses on RNA's role in cellular processes and disease, using NMR spectroscopy, single-molecule methods, and structural biology to study translation regulation and viral RNA mechanisms.
Education:
- PhD in Biophysical Chemistry, University of California, Berkeley (1989)
- BA in Chemistry, Johns Hopkins University (1984)
Research Interests: The Puglisi group investigates RNA structure-dynamics-function relationships, particularly in eukaryotic translation initiation and viral RNA replication. Their work spans from molecular-level NMR/X-ray crystallography to cellular-level impacts, with therapeutic implications for diseases involving RNA dysregulation.
Scientific Awards:
- NIH Director's Transformative R01 Award (2011)
- NIH Merit Award (2011)
- National Academy of Sciences member (2014)
- Alfred P. Sloan Research Fellow (1997)
- David and Lucille Packard Fellow (1994-1999)
- Camille and Henry Dreyfus Teacher Scholar (1993)
Advising & Collaborations: He mentors doctoral students across Bioengineering, Biophysics, Chemical and Systems Biology, Microbiology and Immunology, and Structural Biology PhD programs. His lab collaborates internationally through the International School of Biological Magnetic Resonance (Erice, Italy) with partners like EMFCSC and NSF.
Labs & Teams: Puglisi leads the Stanford Magnetic Resonance Laboratory and co-founded the International School of Biological Magnetic Resonance, training graduate and postdoctoral researchers in biophysical techniques. His team includes alumni transitioning to leadership roles at institutions like UT Southwestern and Fred Hutchinson Cancer Center.
