معرفی
Eric T. Kool is a Professor in the Department of Chemistry at Stanford University, where he holds the George and Hilda Daubert Professorship. He is affiliated with interdisciplinary programs including Bio-X, Biophysics, Stanford Cancer Institute, and the Sarafan ChEM-H initiative.
His research spans organic chemistry, chemical biology, and biophysics, focusing on designing molecular tools for nucleic acid analysis and manipulation. Key contributions include nonpolar nucleoside isosteres, rolling circle amplification, and fluorescent DNA/RNA probes. His work has enabled DNA replication studies without hydrogen bonding and RNA structure mapping in cellular environments.
Recent publications emphasize RNA 2'-OH functionalization, oxidative DNA repair, and CRISPR-Cas9 regulation. His innovations in acylation chemistry and nucleic acid-based data storage highlight his interdisciplinary approach.
Scientific Awards:
- Dreyfus Foundation Teacher-Scholar Award
- Alfred P. Sloan Foundation Fellowship
- ACS Arthur C. Cope Scholar Award
- ACS Pfizer Award
- Murray Goodman Prize
- ACS Breslow Award
- Fellow of AAAS
- Member of the American Academy of Arts and Sciences
Kool has trained over 120 graduate students and postdoctoral researchers, with more than 35 securing academic positions. His lab’s 45 patents underpin five biotechnology companies, and he has delivered over 250 invited lectures globally.
He is also an award-winning educator, twice receiving the Humanities & Sciences Dean's Award for Distinguished Teaching at Stanford for his sophomore organic chemistry courses.
