Jose Rodriguez-Alvarez

Jose Rodriguez-Alvarez is a Visiting Professor at the Dominick P. Purpura Department of Neuroscience at Albert Einstein College of Medicine. His research focuses on understanding synaptic dysfunction and neuronal death mechanisms in neurodegenerative diseases, particularly Alzheimer’s disease (AD). He investigates how beta amyloid (Aβ) oligomers contribute to early cognitive deficits and explores therapeutic targets and biomarkers for early diagnosis and functional recovery.

His research interests center on synaptic plasticity, AMPA receptor regulation, and microRNA biomarkers. He employs experimental AD models to study transcriptional and post-transcriptional gene regulation, neuromuscular unit changes, and angineurin release effects.

Selected publications highlight work on Nr4a2 transcription factors in memory, microRNA biomarkers for Alzheimer’s, and CRTC1’s role in neurodegenerative memory deficits. His studies bridge molecular mechanisms with translational biomarker discovery.

No scientific awards are explicitly mentioned. His work involves collaborations with researchers like Dr. C.A. Saura and Dr. AJ Miñano-Molina, focusing on neurodegenerative pathways and synaptic dysfunction mechanisms.