معرفی
Jorg van Loosdregt is an Associate Professor at UMC Utrecht, affiliated with the Laboratory for Translational Immunology (LTI) and the Center for Molecular Medicine (CMM). His research focuses on molecular pathways in immune-related diseases, particularly Juvenile Idiopathic Arthritis, combining immunology and translational medicine to improve diagnostics and therapies.
- PhD in Molecular Immunology (2011, cum laude), University Medical Center Utrecht
His research explores immune homeostasis, T-cell regulation, and the role of epigenetics and metabolic reprogramming in autoimmune disorders. He investigates how autophagy and epigenetic modifications influence T-cell function in rheumatoid arthritis and pediatric conditions.
Recent publications highlight his work on CD4+ T-cell metabolism, epigenetic regulation, and molecular targets for autoimmune therapies. Studies include glycolytic reprogramming in arthritis, CBP/P300 inhibition effects, and RNA modifications in T-cell responses.
- 2016: Wilhelmina Children's Hospital fellowship (€150,000)
- 2015: Dutch Arthritis Foundation fellowship (€160,000)
- 2014: NWO VENI fellowship (€250,000)
Van Loosdregt leads translational research projects supported by multiple grants and contributes to interdisciplinary studies on immune-driven diseases. His work spans collaborations with the Pediatric Immunology team to develop preventive interventions for autoimmune conditions.
