معرفی
Jonathan Brouillette is an Associate Professor in the Department of Pharmacology and Physiology at the Université de Montréal, where he leads research on Alzheimer’s disease and age-related memory loss. His work focuses on identifying molecular mechanisms underlying neurodegeneration and developing therapeutic interventions. He holds affiliations with the Signal Signaling and Circuitry Research Group (SNC) and the Quebec Interdisciplinary Research Center on the Brain and Learning (CIRCA).
Education:
- PhD in Neuroscience (2001), McGill University
- Postdoctoral training at Yale University (2011) and Université de Lille 2 / Université de Louvain (2007)
Research: Brouillette’s lab uses animal models and molecular biology techniques (e.g., RNAseq, immunohistochemistry) to study amyloid-beta oligomer toxicity, tau propagation, and sleep-cognition interactions. Key interests include neuroligin-1 as a blood biomarker and STEP phosphatase’s role in memory decline.
Grants: He leads projects funded by CIHR, FRQS, and the Weston Brain Institute, totaling over CAD 5M since 2014. Notable grants include studies on amyloid-induced neurodegeneration and neuroligin-1 biomarker development.
Awards: Includes FRQS Junior 2 Award (2020), Alzet-JoVE International Prize (2015), and multiple peer-recognized publications (e.g., Current Biology, PLoS Biology).
Labs & Teams: Directs the Alzheimer’s Disease Neurobiology Lab and collaborates with the CIMA-Q (Early Alzheimer’s Detection Consortium) and the Quebec Sleep Research Network (RQRS).
