معرفی
John Wysolmerski is a Professor of Medicine and Section Chief of Endocrinology and Metabolism at Yale School of Medicine. He is affiliated with the Department of Internal Medicine and holds key roles in the Yale Cancer Center, Yale Stem Cell Center, and the Bone Center. His clinical and research work focuses on endocrine disorders, particularly those involving calcium, bone, and mineral metabolism.
His educational background includes a BS in Biology (1982) and MD (1986) from Yale University, followed by internship and residency at Tufts New England Medical Center.
Dr. Wysolmerski's research explores the biological functions of parathyroid hormone-related protein (PTHrP) and the calcium-sensing receptor in the breast, with a focus on their roles in lactation and breast cancer. His work also investigates cancer-associated hypercalcemia and the brain-breast-bone axis in metabolic regulation. His recent publications span molecular oncology, endocrinology, and physiology, highlighting signaling pathways in breast cancer, calcium dynamics in lactation, and tumor-induced metabolic syndromes.
His research trends emphasize the intersection of endocrinology and oncology, particularly in understanding how hormonal signaling influences tumor progression and metabolic complications.
- Co-Chair, 4th International Symposium on the Calcium Sensing Receptor (2023)
- Co-Chair, Mammary Gland Biology Gordon Research Conference (2013)
- Standing Member, ICER Study Section, NIH (2012)
- President, Interurban Clinical Club (2010)
- Interurban Clinical Club Councilor (2007)
Dr. Wysolmerski has mentored numerous trainees and leads a robust research program supported by institutional and federal funding. He serves on editorial boards including Endocrinology and the Journal of Mammary Gland Biology and Neoplasia, and contributes to national research initiatives through NIH and Gordon Research Conferences. He is actively involved in developing clinical programs such as the Fracture Liaison Service at Yale to improve osteoporosis care.
He leads a multidisciplinary research team focused on endocrine oncology and mineral metabolism, collaborating with experts in molecular biology, oncology, and physiology. His lab is part of the broader Yale research ecosystem, including the Yale Cancer Signaling Networks and the Diabetes Research Center.
