John Iredale

John Iredale is a distinguished academic and administrator currently serving as Pro Vice Chancellor for Health and Life Sciences at the University of Bristol (2016–present) and Director of the NIHR Biomedical Research Centre there. He previously held leadership roles at the University of Edinburgh, including Dean of Clinical Medicine and Director of the MRC Centre for Inflammation Research.

• Education: University of Southampton (1985, Medicine with Clinical Distinction)

Iredale's research focuses on fibrosis reversal mechanisms, macrophage biology, and inflammation in liver disease. His work demonstrated fibrosis reversibility, spurring pharmaceutical investment in antifibrotic therapies. Key discoveries include relaxin's therapeutic potential and macrophage roles in fibrosis resolution.

His publications span Nature journals, Science, JCI, and Proc Natl Acad Sci, with over 20,000 citations and an H-index of 75. Two papers exceed 1,000 citations each.

• Scientific Awards
  • Elected Fellow of the Royal College of Physicians of London (1999)
  • Fellow of the Academy of Medical Sciences (2003)
  • Fellow of the Royal College of Physicians of Edinburgh (2007)
  • Fellow of the Royal Society of Edinburgh (2011)
  • Chair, REF2021 Main Panel A (Medicine, Biomedical Sciences, Life Sciences, Veterinary Medicine)

Iredale has secured lifetime grants exceeding £50M and shaped clinical academic training for medical, dental, and veterinary graduates internationally. He holds leadership roles in organizations like the British Heart Foundation and CRUK Beatson Institute.