John F. Valentine

John F. Valentine, MD, is a Professor of Medicine at the University of Utah School of Medicine, specializing in Gastroenterology within the Division of Gastroenterology, Hepatology and Nutrition. He serves as the Director of the University of Utah Inflammatory Bowel Disease Center, focusing on ulcerative colitis, Crohn's disease, and celiac disease. Dr. Valentine received his M.D. from the University of Texas Medical School at Houston (1985), completed Internal Medicine training at the Medical College of Virginia, and a Gastroenterology fellowship at the University of Florida.

His research centers on inflammatory bowel disease (IBD), including clinical trials, molecular mechanisms, and therapeutic innovations. Key interests include TNF signaling, microbiome dysbiosis, vaccine responses in IBD patients, and novel biologics. Recent work explores epigenetic regulation, kinase inhibitors, and dietary interventions for Crohn's disease.

Dr. Valentine's publications emphasize clinical trials, immunology, and translational research, with trends toward personalized medicine and biomarker discovery. He is a Fellow of the American Gastroenterological Association and has led multicenter studies (e.g., EXPLORER, OPTIMIZE).

He directs the IBD Center, coordinating laboratory research and clinical programs to advance treatment options. No student advisees or part-time status are noted.