John Burke

John Burke is an Associate Professor in the Department of Biochemistry and Microbiology at the University of Victoria, with affiliations spanning structural biology, lipid signaling, and drug discovery. His research focuses on the structural and functional regulation of phosphoinositide kinases, particularly their roles in cancer, neurodegenerative disease, and infectious processes.

• Key research themes: phosphoinositide signaling, protein-membrane interactions, HDX-MS analysis, and structure-based drug design.
• Recent trends: Investigations into GTPase regulation, PI3Kγ/PI4K inhibitors, and mechanisms of lipid homeostasis in disease.

Scientific awards include recognition as an MSFHR Scholar and membership in the Royal Society of Canada’s College of New Scholars, Artists, and Scientists.

Grants and collaborations highlight partnerships with CIHR, NSERC, and CRS, along with interdisciplinary work in oncology, virology, and metabolic disorders.