John A. Corbett

John A. Corbett, PhD, serves as Professor and Chair of the Department of Biochemistry at the Medical College of Wisconsin (MCW), where he joined in 2010 after holding the Nancy R. and Eugene C. Gwaltney Family Endowed Chair in Juvenile Diabetes Research at the University of Alabama at Birmingham (2007-2010). Previously, he rose from Assistant Professor to Professor in Biochemistry at Saint Louis University (1995-2005).

His academic credentials include a BS in Chemistry from Saint Norbert College (1985) and a PhD in Biochemistry from Utah State University (1990), followed by postdoctoral training in Pathology at Washington University School of Medicine (1990-1994).

Dr. Corbett's research centers on pancreatic beta cell mechanisms in diabetes pathogenesis, with three core programs: (1) nitric oxide's dual role in beta cell toxicity and protection against cytokine damage; (2) viral infection impacts on macrophage activation and beta cell dysfunction; and (3) mitochondrial DNA mutation consequences on beta cell failure. His work integrates molecular, cellular, and transgenic approaches to dissect diabetes etiology.

Analysis of his 2022-2025 publications reveals dominant themes in beta cell inflammatory responses, BET bromodomain inhibition, and mitochondrial DNA integrity. His research bridges immunology, molecular biology, and endocrinology to identify therapeutic targets for diabetes, with consistent focus on oxidative stress pathways and transcriptional regulation in islet cells.

No scientific awards are documented in the source material.

As department chair and principal investigator, Dr. Corbett leads a diabetes-focused research laboratory at MCW. While specific grant details and team composition remain unreported, his extensive publication record indicates active mentorship of graduate students and postdoctoral researchers within the Biochemistry Department.