معرفی
Jin-Young Choi is a Research Scientist in the Craft laboratory at Yale School of Medicine's Department of Internal Medicine, specializing in the Section of Rheumatology, Allergy, and Immunology. Her research focuses on understanding autoimmune mechanisms, particularly lupus nephritis and the role of T cells in renal injury. She completed her PhD at Oregon State University (2000) under Dr. Nancy Kerkvliet, studying dioxin-induced immune dysfunction, and later joined Dr. Joseph Craft’s lab at Yale, supported by an Arthritis Foundation fellowship. Her work investigates T cell differentiation and effector functions in autoimmunity and infection.
Key areas of research include follicular helper T cells (TFH), CXCR5+ memory T cells, and natural Th17 cells. Her studies link T cell subsets to disease activity in systemic lupus erythematosus and explore therapeutic interventions using mouse models. Collaborations with Dr. Craft and others have yielded insights into NFAT signaling pathways and immune cell infiltration in autoimmune pathogenesis.
Publications highlight her contributions to understanding TFH cell biology, T cell-mediated renal damage, and cytokine regulation. Her work bridges basic immunology with clinical autoimmune diseases, emphasizing translational applications. She is affiliated with the Craft Lab and multiple Yale departments, contributing to interdisciplinary research in rheumatology and immunology.
