Jin Xu

Jin Xu is a Professor in the Department of Chemistry at the University of Massachusetts Lowell, affiliated with the Kennedy College of Sciences. His research focuses on protein analysis, biopharmaceutical discovery, and structural studies of therapeutic proteins. He has collaborated with over 50 biopharmaceutical companies, addressing challenges in protein folding, aggregation, and posttranslational modifications. His expertise spans traditional and emerging protein therapeutics like bispecific antibodies and antibody-drug conjugates.

Education:

• B.S. in Biochemistry from East China University of Science and Technology (ECUST), Shanghai, China
• Ph.D. in Biochemistry from the University of North Texas
• Postdoctoral Fellowship in Biochemistry/Biophysics at the University of North Texas

Research Interests:

• Structure-function relationships in therapeutic proteins
• Protein aggregation mechanisms and adverse effects
• Role of posttranslational modifications
• Optimization of biopharmaceutical manufacturing processes
• Structural characterization of fusion proteins and ADCs

Publications reflect interdisciplinary research in protein dynamics, biophysical techniques, and biopharmaceutical applications. Collaborations emphasize translating fundamental discoveries to industry challenges in drug development and quality control.

Labs/Teams: Leads a lab with industry partnerships, pioneering structural studies for biopharmaceutical innovation.