Jie Zheng

Jie Zheng is a Research Fellow in the Department of Internal Medicine at Yale School of Medicine, Yale University. Their research focuses on the interplay between environmental chemicals, metabolic disorders, and oncological mechanisms, with a strong emphasis on analytical techniques such as mass spectrometry and metabolomics. Key areas include the effects of PFAS on cancer progression, lipid metabolism in metabolic dysfunction-associated steatohepatitis, and immune responses in gastrointestinal diseases.

Publications span topics like PFAS carcinogenicity, xenograft tumor biology, and development of advanced analytical platforms for chemical screening. Methodological contributions include novel strategies for metabolic flux analysis and toxin detection.

• Research highlights PFAS-induced cancer cell migration and ferroptosis in colorectal cancer.
• Explores CIDEB's role in hepatic lipid regulation and insulin resistance.
• Advances in chemical isotope labeling and non-targeted toxicity frameworks.