معرفی
Jianying Dong is an Associate Research Scientist in the Department of Endocrinology at Yale School of Medicine, Yale University. Her research focuses on metabolic disorders, insulin resistance, and molecular mechanisms underlying energy homeostasis. She collaborates with prominent researchers like Gerald I. Shulman, investigating topics such as leptin signaling, mitochondrial function, and dietary-induced metabolic changes. Key contributions include studies on the role of mitochondrial enzymes in gluconeogenesis and the impact of genetic deficiencies on obesity and insulin sensitivity.
Her work employs mouse models to explore pathways related to fatty acid metabolism, gut-derived signaling molecules, and aging effects on metabolic processes. Notable publications address leptin’s role in body temperature regulation, mitochondrial dysfunction in liver steatosis, and the protective effects of n-3 fatty acids against insulin resistance. Dong’s interdisciplinary approach bridges endocrinology, molecular biology, and physiology, contributing to advancements in diabetes and metabolic disease research.