معرفی
Jiankan Guo is an Assistant Professor in the Department of Internal Medicine (Nephrology) at Yale School of Medicine. His research focuses on kidney development, cellular repair mechanisms, and stem cell-mediated renoprotection.
Key research themes include:
- Molecular regulation of metanephric mesenchyme-ureteric bud interactions during kidney formation
- Immune cell-tubule cross-talk in AKI-to-CKD transition
- Role of stromal cell populations in kidney injury repair
- Development of embryonic stem cell differentiation protocols toward renal lineages
Recent publications (2022–2024) highlight his work on:
- VCAM-1 signaling in failed tubule recovery
- Myofibroblast-macrophage interactions during repair
- Arginase-1 expression in injured renal cells
- Immune-mediated tubule atrophy mechanisms
Collaborators include prominent nephrologists and stem cell researchers like Lloyd G. Cantley, Diane Krause, and Leyuan Xu. While no formal awards are listed, his sustained publication record in high-impact journals (Journal of the American Society of Nephrology, American Journal of Physiology) demonstrates scholarly impact.
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