معرفی
Gilbert Moeckel, MD, PhD, is a Professor of Pathology at Yale School of Medicine, where he serves as Director of the Renal Pathology and Electron Microscopy Laboratory and Director of the Renal & Genitourinary Fellowship Program. He is a key figure in clinical renal pathology and translational research at Yale, with strong affiliations in the Department of Pathology and collaborations across nephrology and internal medicine.
- MD and PhD from Ludwig-Maximilians-Universität München
- Residency and Fellowship at the University of Arizona
- Former faculty at Vanderbilt University
- Board-certified by the American Board of Pathology
- Fellow of the American Society of Nephrology
Dr. Moeckel's research is centered on the molecular mechanisms of kidney injury, repair, and the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). His lab investigates the role of DDT/MIF2 signaling and intrinsic progenitor cells (such as pericytes) in tubular regeneration and fibrosis. He is deeply involved in identifying novel biomarkers for kidney diseases, including urinary CXCL9 for acute interstitial nephritis, and in understanding the pathogenesis of diabetic nephropathy and glomerular diseases.
His recent publications reveal a strong focus on biomarker discovery, mechanistic pathways in kidney injury, and clinical applications in nephrology. He frequently collaborates with leading researchers such as Lloyd Cantley, Gary Desir, and Shuta Ishibe, contributing to high-impact studies in journals like the Journal of the American Society of Nephrology and the Journal of Clinical Investigation. His work spans from basic molecular biology to clinical trial design, including a phase 2 trial on metformin for focal segmental glomerulosclerosis.
- Fellow, American Society of Nephrology
- Diplomat, American Board of Pathology
- Recipient of federal and private industry research grants
Dr. Moeckel has been actively mentoring trainees and leading the renal fellowship program. He has secured grant funding to support his research on kidney repair mechanisms and biomarkers. His lab, the Moeckel Lab, is a hub for innovation in renal pathology, utilizing electron microscopy and molecular techniques to advance diagnostic and therapeutic strategies. He is also involved in educational initiatives and clinical diagnostics, contributing to teaching cases and diagnostic guidelines for complex kidney diseases.
He leads the Moeckel Lab at Yale, located in the Brady Memorial Laboratory, which focuses on experimental models of kidney injury and human tissue analysis. The lab is part of a broader network of renal and translational research at Yale, collaborating with the Yale Center for Clinical Investigation (YCCI) and the Nephrology Division.
حوزههای پژوهشی