معرفی
Shuta Ishibe is a Professor of Medicine (Nephrology) at the Yale School of Medicine, serving as Interim Section Chief and Director of the Undergraduate Summer Research Program. His research focuses on podocyte biology in proteinuric kidney diseases, particularly mechanisms of endocytosis and cell-matrix interactions.
- Education: MD (University of Texas Southwestern, 1997), BA (Rice University, 1993)
- Honors: Distinguished Researcher Award (ASN 2020), Member of ASCI (2020), Gottschalk Award (ASN 2007)
Dr. Ishibe’s lab investigates how podocyte injury leads to chronic kidney disease, using mouse genetic models to study focal adhesion proteins (FAK), endocytic machinery (synaptojanin, dynamin), and their roles in nephrotic syndrome. His work has identified FAK inhibitors as potential therapeutics and collaborates with Novartis and Dr. Pietro De Camilli.
Recent publications span podocyte cytoskeletal regulation, genetic models, APOL1 risk variants, and YAP signaling in mechanosensing. Key research themes include endocytosis, focal adhesions, actin dynamics, and translational approaches to proteinuria.
- Scientific Awards
- Distinguished Researcher Award (2020, ASN)
- Member, American Society for Clinical Investigation (2020)
- Gottschalk Award (2007, ASN)
- Alpha Omega Alpha (1997)
- Cum Laude (1993, Rice University)
His laboratory (Ishibe Lab) collaborates with researchers like Xuefei Tian, Patricia Bunda, and Gilbert Moeckel. Future work aims to expand understanding of podocyte cell-matrix biology and identify novel disease mutations through human sample analysis.
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