معرفی
Dennis G Moledina is an Associate Professor of Medicine in the Section of Nephrology at the Yale School of Medicine. He serves as Director of the Research Fellowship in Nephrology, Vice Chief for Clinical and Translational Research in Nephrology, and Director of the Yale Kidney BioBank. He is actively involved in clinical care at Yale-New Haven Hospital and leads a robust research program focused on acute kidney injury and interstitial nephritis.
- Associate Professor of Medicine (Nephrology), Yale School of Medicine
- Director, Research Fellowship, Nephrology
- Vice Chief for Research (Clinical/Translational), Nephrology
- Director, Yale Kidney BioBank
- Primary Affiliation: Department of Internal Medicine, Yale School of Medicine
- Additional Affiliations: Cancer Immunology, Clinical and Translational Research Accelerator (CTRA), Human and Translational Immunology Program, Yale Cancer Center, Yale Medicine
Dr. Moledina’s research is centered on acute kidney injury (AKI) and acute interstitial nephritis (AIN), with a strong emphasis on biomarker discovery and translational research. His work aims to develop non-invasive diagnostic tools using urine biomarkers such as CXCL9, TNF-α, and IL-9, and to build predictive models using electronic health record data. His research bridges clinical nephrology with immunology and data science.
The recent publications highlight a consistent focus on diagnosing and prognosticating AIN using urinary biomarkers and EHR-based models. There is a strong trend toward precision medicine in nephrology, leveraging multicenter collaborations and biorepositories like the Yale Kidney BioBank. His work integrates immunology, clinical informatics, and epidemiology to improve patient outcomes.
His scientific awards include:
- Fellow, American Society of Nephrology (FASN), 2021
- K23 Mentored Patient-Oriented Career Development Award, NIH/NIDDK, 2018
- American Heart Association Career Development Award, 2018
- KPMP Opportunity Pool Travel Grant, 2018
- Top-rated Abstract, National Kidney Foundation, 2024
Dr. Moledina has received independent research funding from the NIH and is a co-investigator in major multicenter consortia, including the Kidney Precision Medicine Program (KPMP) and Care of Outpatients with Acute Kidney Injury (COPE-AKI). He mentors a large collaborative research network and leads key committees in professional organizations such as the American Society of Nephrology. His leadership roles in research fellowships and biorepository development underscore his commitment to training and infrastructure building in nephrology.
He directs the Yale Kidney BioBank, a biorepository that has collected samples from over 1,400 participants with kidney biopsy-confirmed diagnoses since 2015. This resource supports translational research in kidney disease and enables biomarker validation studies. He is also actively involved in the Clinical and Translational Research Accelerator (CTRA) and leads initiatives in cancer immunotherapy-related kidney injury.