Jesús de la Cruz Díaz

Jesús de la Cruz Díaz is a Professor in the Department of Genetics at the University of Seville, Spain. He leads the research group 'Gene Expression in Eukaryotes' and specializes in ribosome biogenesis, focusing on protein-RNA interactions and assembly mechanisms in Saccharomyces cerevisiae. His work is supported by numerous grants, including PID2022-136564NB-I00 (Molecular contribution of RNA helicases) and TED2021-129601B-I00 (translation-based circular economy strategies).

Research interests include ribosomal protein function, RNA helicases, and the interplay between ribosome assembly and cellular processes like cancer and hereditary diseases. He has directed multiple PhD theses, including studies on RNA helicases (Julia Mª Contreras) and ribosomal proteins (Sara Martín Villanueva).

Key contributions include discoveries on ribosomal protein roles in subunit maturation, ubiquitin regulation in ribosome function, and the impact of translational machinery defects on disease. His lab explores translational control, pre-ribosomal particle dynamics, and the structural basis of ribosome assembly.

Grants span 30 years, with ongoing projects on ribosome synthesis homeostasis and translational strategies for biotechnology. Collaborations include work with institutions in Germany (Dieter Kressler) and Switzerland (Ed Hurt). No awards are explicitly mentioned, but his extensive publication record (over 150 articles) reflects sustained research impact.