معرفی
Jessica C. Seeliger is an Associate Professor in the Department of Pharmacological Sciences at Stony Brook University's Renaissance School of Medicine, with secondary appointments in the Department of Molecular Genetics and Microbiology and as Affiliated Faculty in the Department of Chemistry. Her laboratory focuses on understanding the molecular mechanisms of bacterial membrane biogenesis, particularly in Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis.
Dr. Seeliger received her A.B. in Chemistry from Harvard University in 2000, her MPhil in Chemistry from the University of Cambridge in 2001, and her Ph.D. in Chemistry from Stanford University in 2007. She completed postdoctoral training with Carolyn Bertozzi at the University of California, Berkeley before establishing her independent research program at Stony Brook University in Fall 2010.
Her research program investigates lipid membranes in bacterial pathogens, with particular emphasis on mycobacteria. The Seeliger lab applies biochemical, microbiological, and biophysical approaches to address fundamental questions about mycomembrane assembly, lipid transport mechanisms, and how these pathways contribute to bacterial growth, division, and virulence. They also develop chemical tools to study processes in the bacterial cell envelope specifically and accurately. Current research directions include understanding mycomembrane assembly mechanisms, investigating how membrane properties affect antibiotic susceptibility, and developing strategies to subvert lipid biosynthesis for antimicrobial therapy.
Dr. Seeliger's research has been recognized with prestigious awards including the Robbee Baker Kosak Leadership Prize from the Hertz Foundation and NIH funding for the Chemical Biology Training Program which she co-directs. Her work has been supported by Stony Brook University, SUNY, the Stony-Wold Herbert Fund, the American Lung Association, the Burroughs Wellcome Fund, NSF, NIGMS, and NIAID.
Dr. Seeliger is an active mentor who has guided numerous graduate students, postdoctoral researchers, and undergraduate trainees. Her lab has a collaborative environment with members possessing diverse expertise ranging from synthetic chemistry to biophysics to microbiology. The lab maintains active collaborations within and outside Stony Brook University, including international partnerships.
The Seeliger lab operates from the Centers for Molecular Medicine at Stony Brook, with office space in room 448 and laboratory space in room 435. They welcome new members interested in exploring the intersection of chemistry and biology in the context of bacterial pathogenesis.
