معرفی
Dr. Jesse Bloom is a Professor in the Basic Sciences Division at Fred Hutchinson Cancer Research Center and a Professor in the Herbold Computational Biology Program at the University of Washington's Public Health Sciences Division. He is also an Investigator at the Howard Hughes Medical Institute. His research focuses on viral evolution, particularly influenza and SARS-CoV-2, using experimental and computational methods to study mutation impacts on viral function, immune escape, and global spread. Bloom's work bridges molecular biology, epidemiology, and computational science, with a focus on understanding how viruses evolve to evade immunity and adapt to new hosts.
- Education: PhD in Chemistry (Caltech), MPhil in Theoretical Chemistry (Cambridge), BS in Biochemistry (University of Chicago)
- Affiliations: HHMI Investigator, Fred Hutch Basic Sciences Division, UW Herbold Computational Biology Program
- Key Research Themes: Deep mutational scanning, antibody escape mechanisms, viral evolutionary constraints, influenza/SARS-CoV-2 dynamics
His lab develops tools like dms-viz and seqneut-pipeline to analyze viral evolution at scale. Recent studies include mapping SARS-CoV-2 escape mutations and influenza antigenic evolution. Bloom has advised over 30 graduate students and postdocs, many now leading roles in academia and industry.
Scientific Achievements: HHMI Investigator (2018), AAAS Fellow (2025), pioneering work in viral escape prediction and antibody neutralization assays. His lab's software (alignparse, dms-vep-pipeline) are widely used in virology and computational biology.
