معرفی
Jerome Le Nours is an Associate Professor in the Department of Biochemistry and Molecular Biology at Monash University, within the Faculty of Medicine, Nursing and Health Sciences. He is also an Australian Research Council (ARC) Future Fellow and an independent group leader at the Monash Biomedicine Discovery Institute, where he leads a research program focused on structural and comparative immunology.
- Position: Associate Professor
- Institution: Monash University
- School: Faculty of Medicine, Nursing and Health Sciences
- Department: Biochemistry and Molecular Biology
- Research Institute: Monash Biomedicine Discovery Institute
- Status: ARC Future Fellow (2017)
Jerome earned his PhD in Structural Biology from the University of Copenhagen (Denmark) in 2005, after initial training in chemistry at the University of Brest (France). He conducted postdoctoral research at the University of Auckland (New Zealand), studying Mycobacterium tuberculosis protein structures, before joining Monash University in 2008 as a research fellow.
His research focuses on the structural mechanisms of immune recognition, particularly in the context of non-classical MHC-mediated T-cell immunity. He investigates how non-peptidic antigens are recognized by T cells via MHC-like molecules such as MR1 and CD1a, combining structural biology, comparative immunology, chemistry, and advanced imaging techniques. His work has been published in top-tier journals including Nature, Nature Immunology, Nature Communications, and Journal of Experimental Medicine.
The most recent publications highlight his contributions to understanding MR1-mediated vitamin B6 antigen presentation, lipid antigen recognition in tumor immunity, and atypical T-cell receptor engagement mechanisms. These studies reveal novel insights into innate-like T-cell responses, with implications for cancer immunotherapy and autoimmune diseases.
Jerome has received the prestigious Australian Research Council Future Fellowship in 2017. His editorial and professional service includes roles as Associate Editor for Frontiers in Immunology and Guest Editor for International Journal of Molecular Sciences.
- Australian Research Council (ARC) Future Fellowship (2017)
He actively participates in the scientific community, presenting at major conferences such as the International Union of Crystallography and the European Congress of Immunology. His research group accepts PhD students, and he contributes to peer review and advisory panels. He has also been featured in media outlets for discoveries related to T-cell lineages and allergic responses.
