معرفی
Dr. Adam Shahine is a Senior Research Fellow and Group Leader in the Immunity Program at Monash University's Biomedicine Discovery Institute. He holds dual affiliations with the Department of Biochemistry and Molecular Biology and leads the lipid-mediated structural immunology lab. His work focuses on understanding lipid antigen presentation by CD1 molecules in T-cell immunity, with applications in autoimmune disease and bacterial infection research.
Education: BSc in Biochemistry/Microbiology/Biotechnology from University of Melbourne (2008), M.BSc from Monash University (2009), PhD in Structural Biochemistry from Monash University (2016) under Prof. Jamie Rossjohn and A/Prof Travis Beddoe.
Research interests include structural immunology, CD1 molecule function, and T-cell receptor recognition mechanisms. He employs advanced techniques like x-ray crystallography and mass spectrometry. Current projects investigate Group 1 CD1 molecules' roles in Mycobacterium tuberculosis infection and autoimmune conditions such as psoriasis.
Key publications (2023-2020) explore CD1 lipidome dynamics, therapeutic antibody design, and bacterial antigen presentation mechanisms. Notable awards include NHMRC Emerging Leader Fellowship (2024-2028) and ARC DECRA Fellowship (2021-2023).
Leadership & grants: Principal Investigator on $3.4M ARC project (2021-2024) and NHMRC Emerging Leader Fellowship funding. Advises PhD students and mentors early-career researchers. Active in organizing conferences like the 12th EMBO CD1/MR1 conference (2022).
Laboratory: Leads a team focused on translating structural biology insights into novel therapeutics targeting immune disorders and infections.
