معرفی
Dr. Jennifer Malcolm serves as a Lecturer at the University of Glasgow's Dental School within the School of Medicine, Dentistry & Nursing. Based at Glasgow Dental School, Level 9, L14, she maintains an active research program investigating the connections between oral immunity and systemic diseases, particularly rheumatoid arthritis. Her work bridges clinical dentistry with fundamental immunological research, focusing on how oral pathogens subvert host immune responses.
Dr. Malcolm earned her 1st Class BSc/Hons in Microbiology from Glasgow Caledonian University before completing her PhD at the University of Glasgow. Her academic journey includes postdoctoral research at the University of Glasgow's School of Infection and Immunity, where she developed therapeutic target discovery pipelines for periodontal disease and investigated immune tolerance mechanisms related to bacterial citrullination.
Her primary research interests focus on oral immunology, particularly the relationship between periodontal disease and rheumatoid arthritis. She investigates how oral bacteria exploit innate immunity to subvert adaptive immune responses and impact immune tolerance in the oral mucosa. Her work spans host-pathogen interactions in oral biofilms, cellular mechanisms of periodontal disease, and the systemic implications of oral inflammation.
Analysis of her publication record reveals a clear trajectory from fundamental oral microbiology toward the immunological connections between oral health and systemic autoimmune conditions. Her most recent work (2023-2024) increasingly focuses on citrullinated peptides, T cell activation, and the oral-systemic disease link, particularly with rheumatoid arthritis. Alongside this research, she has maintained a parallel interest in dental education, publishing on virtual learning adaptations during the pandemic.
Dr. Malcolm currently holds significant research funding including a 2025-2027 Academy of Medical Sciences grant investigating 'Immunopathogenic mechanisms and MHCII neoepitopes linking porphyromonas gingivalis infection with autoreactive CD4 T cell activation' and a 2021-2022 Oral and Dental Research Trust grant on 'The interplay between stress, oral biofilms and oral epithelial barrier function.'
She supervises doctoral students including Binsaif, Nasser Fahad M (investigating intracellular immune signaling pathways in oral epithelia) and Piela, Krystyna (researching barrier integrity in the oral cavity). Her educational contributions include developing Microsoft Teams applications for small group learning and virtual microscopy adaptations for dental education during the pandemic.
