Jennifer L. Clarke

Jennifer L. Clarke, MD, MPH is a Professor of Clinical Neurology and Neurological Surgery at the University of California, San Francisco (UCSF). She serves as Principal Investigator at the UCSF Brain Tumor Research Center and is a key member of the Weill Institute for Neurosciences. Her clinical practice focuses on neuro-oncology at 400 Parnassus Ave., San Francisco, CA.

Education:

• MD from UCSF School of Medicine (2002)
• MPH in Health Policy and Management from UC Berkeley (2001)
• Internship in Internal Medicine at Physicians Regional Medical Center (2003)
• Residency in Neurology at UCSF (2006)
• Fellowship in Neuro-Oncology at Memorial Sloan-Kettering (2008)

Research Interests center on cell therapy, precision medicine, and immunomethylomics for glioma treatment. She pioneers molecular imaging techniques to analyze tumor responses and explores DNA damage repair variants as survival predictors.

Clinical Trials include neoadjuvant anti-PD1 immunotherapy, vorasidenib/ivosidenib combination trials, and synNotch CAR T-cell therapy for glioblastoma. Her work spans 15+ recent publications on glioma evolution and precision interventions.

Affiliations include membership in the American Academy of Neurology, American Society of Clinical Oncology, and Society for Neuro-Oncology.