Jeffrey M. Purkerson

Jeffrey M. Purkerson, Ph.D., is a researcher affiliated with the University of Rochester, School of Medicine and Dentistry, Department of Pediatrics, Neonatology. His academic career spans decades of research in cell biology, physiology, and immunology related to renal function and immune regulation.

Education:

• Ph.D. in Pharmacology from University of Virginia (1991)
• B.S. in Biochemistry from California Polytechnic State University (1986)
• Postdoctoral Fellowships in Molecular Genetics and Microbiology at University of Massachusetts Medical Center (1994-1995) and Immunoinflammatory Diseases Research at Searle Research and Development, Monsanto Company (1991-1993)

Research Interests: Dr. Purkerson's work focuses on the cell biology and physiology of carbonic anhydrases, alongside renal epithelial cell responses to acid-base disturbances. His studies explore mechanisms like proton pump dynamics, epithelial differentiation, and immune signaling pathways in contexts such as metabolic acidosis and immunology.

Publications: His research has contributed to understanding renal adaptations (e.g., cortical collecting duct changes, intercalated cell subtypes), antimicrobial peptide production, and immune regulation via CD40L/CD40 interactions. Publications span 2018 to 2000, with recurring themes in Renal Physiology, Cell Signaling, and Immune Response.

Collaborations: He has co-authored studies with experts in nephrology and immunology, including Schwartz GJ, Al-Awqati Q, and others.