معرفی
Jeffrey D. Macklis is the Max and Anne Wien Professor of Life Sciences at Harvard University’s Department of Stem Cell and Regenerative Biology and a Professor of Neurology and Neurosurgery at Harvard Medical School (HMS). He serves on the Executive Committee of the Harvard Stem Cell Institute (HSCI) and previously directed the MGH-HMS Center for Nervous System Repair (2002–2011). His research focuses on neural development, stem cell biology, and regenerative approaches for neurodegenerative diseases like ALS and Huntington’s disease.
Education:
- B.S. in Bioelectrical Engineering and Literature from MIT
- M.D. from Harvard Medical School (Harvard-MIT HST Program)
- Ph.D. in Biological Engineering from MIT
- Postdoctoral training in developmental neuroscience at HMS
Research Interests: The Macklis Lab investigates molecular controls of neuron subtype development, axon guidance, and neural regeneration. Key areas include:
- Directed differentiation of pluripotent cells for therapeutic screening
- Mechanisms of neuronal vulnerability in ALS, HSPs, and autism spectrum disorders
- Subtype-specific axon regeneration in spinal cord injuries
Awards:
- Rita Allen Foundation Scholar (2003)
- NIH Director’s Innovation Award (2006)
- Allen Distinguished Investigator (2015)
Affiliations & Roles:
- Consultant Neurobiologist/Neurologist at Massachusetts General Hospital (MGH)
- Executive Committee Member, Harvard Stem Cell Institute
- Faculty in Harvard’s Neuroscience, Developmental & Regenerative Biology, and Biological & Biomedical Sciences programs
- Member of Harvard-MIT Health Sciences and Technology (HST)
His work bridges basic science and clinical applications, with a focus on translating developmental neurobiology into therapies for nervous system disorders.
