Jean-Pierre Bazureau

Jean-Pierre Bazureau is a Full Professor at the Rennes Institute of Chemical Sciences (ISCR), University of Rennes 1, France, where he has been a key researcher since 2002. He earned his Ph.D. and Habilitation in Chemical Sciences from the same institution and has held academic positions continuously since 1991.

• Affiliation: University of Rennes 1
• School: Rennes Institute of Chemical Sciences (ISCR), UMR CNRS 6226
• Role: Full Professor (since 2002), former Associate Professor (1991–2001)
• Location: Beaulieu 10A, Office 207, Rennes, France
• Contact: jean-pierre.bazureau@univ-rennes.fr

Education:

• Habilitation in Chemical Sciences (Organic Chemistry), University of Rennes 1, 1997
• Ph.D. in Organic Synthesis, University of Rennes 1, 1987
• Master of Science in Organic Chemistry, University of Rennes 1, 1984

Research Interests:
Jean-Pierre Bazureau's research is centered on the development of bioactive molecules for therapeutic applications. His work spans medicinal chemistry, organic synthesis, and chemical biology. Key areas include:

• Inhibitors of Store Operated Calcium Entry (Orai1) for cancer therapy
• Mitochondrial ion channel inhibitors in oncology
• Protein kinase (PKs) inhibitors targeting Alzheimer’s disease and Down syndrome (via the Leucettine program)
• Fluorescence probes to study molecular mechanisms in cancer
• Microwave-assisted organic chemistry and scale-up processes
• Chemical tools derived from ionic liquids applied to organic synthesis

Scientific Output and Recognition:
With over 120 peer-reviewed publications, 28 invited talks, and 68 oral/keynote presentations, Bazureau is a recognized figure in synthetic and medicinal chemistry. He has authored six book chapters, holds five patents, and has supervised 19 Ph.D. students and 15 postdoctoral researchers.

• Awards:
  • Top-50 Tetrahedron Most Cited Paper (2003–2006 and 2004–2007)
  • Thomson Reuters 2003 Award
  • 2019 Laureate of the Fondation Entreprises Grand Ouest BPO for the NanoFluoInCa project

Leadership and Service:
He founded and leads the S2 Wave platform in ScanMAT UMS 2001 CNRS. He served on the ISCR Council (2012–2016), managed the Master’s program in Analytical Chemistry (2007–2013), and was a scientific advisor for ManRos Therapeutics (2009–2014). He is an Editorial Advisory Board member for Pharmaceuticals (MDPI) and a scientific expert for national and international agencies (ANR, HCERES, EEC, etc.).

Collaborations:
He maintains active international collaborations with researchers in Ivory Coast, Tunisia, Brest, Roscoff, Tours, and Rennes, focusing on drug discovery, biological evaluation, and platform development.