معرفی
Jean-Michel Fustin is a UKRI Future Leaders Fellow at the University of Manchester, Division of Diabetes, Endocrinology & Gastroenterology. His roles include leading research on circadian rhythms and methyl metabolism. He has held positions as Associate Professor at Kyoto University (2018-2020) and Adjunct Lecturer there (2014-2018). He earned a PhD from the University of Aberdeen (2008) and a Habilitation from the University of Namur (2000).
Education:
- PhD: Regulation of mammalian Cryptochrome 1 gene expression by melatonin and the circadian clock, University of Aberdeen (2004-2007)
- Habilitation & PGCE, University of Namur (2000)
Research Interests: His work focuses on the intersection of circadian biology, methylation pathways, and metabolic regulation. Key areas include:
- Circadian clock mechanisms and their disruption by metabolic changes
- m6A RNA methylation's role in gene expression timing
- Impact of dietary nutrients (e.g., methionine/choline) on circadian rhythms
- Chronobiological applications in drug delivery and nanoparticle design
Recent Article Trends: Recent work emphasizes dietary interventions' effects on circadian rhythms, nanoparticle systems for neural delivery, and molecular mechanisms linking SAMe metabolism to methylation inhibition. His studies span basic biology to translational applications in health and disease.
Awards:
- UKRI Future Leaders Fellowship (2019)
- 26th Kato Memorial Research Grant (2014)
- Mochida Memorial Foundation Award (2014)
Advising & Grants: He mentors PhD student Jessica Treeby and leads the Centre for Biological Timing project at Manchester. His grants include UKRI funding and international collaborations in Japan and Europe.
Labs & Teams: His lab investigates circadian systems, with a focus on methyl metabolism's role in healthspan and disease. Collaborations include Kyoto University, Takeda Science Foundation, and others.
