Jean McBryan

Dr. Jean McBryan is a Lecturer at the Royal College of Surgeons in Ireland (RCSI), based in the Department of Molecular Medicine. Her research focuses on breast and colorectal cancer, particularly estrogen signaling pathways and endocrine therapy resistance. She holds a PhD in Pharmacology from University College Dublin and a Postgraduate Diploma in Medical Education from RCSI.

Her academic career includes roles as an Honorary Lecturer in Surgery and a Postdoctoral Research Scientist. Her research spans breast cancer metastasis, hormonal influences in colorectal cancer, and the mechanisms underlying treatment resistance. Key areas include the estrogen signaling pathway in endocrine therapy adaptation and sexually dimorphic protection in colorectal cancer.

Dr. McBryan's work is supported by grants from institutions like the Irish Cancer Society and Breast Cancer Ireland. She supervises research on endocrine modulation in colorectal cancer progression. Professional memberships include the European Association for Cancer Research and The Physiological Society.

Her publications (27 total) explore topics such as proteomic profiling of breast cancer cells, GPER receptor effects in colon cancer, and biomarkers for endocrine resistance. Ongoing projects include investigating dormant breast cancer cells and circRNA as ovarian cancer biomarkers.