معرفی
Jean-Ju Chung is an Associate Professor at the Yale School of Medicine, affiliated with the Department of Cellular and Molecular Physiology and Department of Obstetrics, Gynecology & Reproductive Sciences. She directs the Ion Channels & Reproductive Physiology Lab and holds a PhD in Neuroscience and Biochemistry from Johns Hopkins University (2007), preceded by an MS in Neuroendocrinology and BS in Molecular Biology from Seoul National University.
- Research Focus: Sperm calcium signaling via CatSper channels, membrane microdomains, and redox regulation of fertility
- Technologies: STORM microscopy, cryo-electron tomography, molecular genetics
Her work reveals how CatSper channels form four linear calcium domains to orchestrate flagellar motility and fertility, with implications for IVF optimization and non-hormonal contraception. Recent studies include AI-driven evolutionary analysis of fertilization mechanisms and 3D structural mapping of channel complexes.
Scientific Awards:
- Highly Cited Researcher (2019, 2020)
- Janice Bahr Junior Scientist Travel Award (2020)
- Rudolf J. Anderson Fellowship (2018)
Her lab collaborates with experts in structural biology (Huafeng Wang), genomics (Francesc Lopez-Giraldez), and clinical genetics (Kaya Bilguvar). She has received continuous NIH funding for investigations into channelopathies in infertility and redox-controlled spermatogenesis.
