معرفی
Jason McLellan is an Associate Professor of Molecular Biosciences and the Robert Welch Chair in Chemistry at the University of Texas at Austin, where he leads research in structural biology and vaccine development. His work has been instrumental in the design of vaccines for SARS-CoV-2 and respiratory syncytial virus (RSV).
McLellan earned his B.S. in Chemistry with a biochemistry emphasis from Wayne State University, followed by a Ph.D. from Johns Hopkins University School of Medicine and postdoctoral training at the NIH Vaccine Research Center. His academic journey laid the foundation for breakthroughs in stabilizing viral spike proteins, enabling rapid vaccine development.
His research focuses on structure-based vaccine design, particularly targeting coronaviruses and RSV. By elucidating the structure and function of viral surface proteins, his lab aims to create broad-spectrum vaccines and prepare for future outbreaks. His work bridges biochemistry, virology, and immunology, with strong implications for global public health.
Although specific publications are not listed in the source text, his research trajectory centers on viral spike proteins, protein stabilization, and antibody response—key areas in modern vaccinology.
- 2020 Golden Goose Award
- National Inventors Hall of Fame Inductee (2025)
McLellan has advised major public discussions on vaccine science, including a virtual town hall with Wayne State University leadership. His research is supported by federal and institutional funding, though specific grants are not detailed in the text. He is actively mentoring the next generation of scientists through teaching courses such as Methods in Structural Biology and Advanced Biochemistry.
His laboratory focuses on structural characterization of viral glycoproteins and engineering novel vaccine candidates. The team employs cryo-electron microscopy, X-ray crystallography, and protein design techniques to advance vaccine platforms for RSV and emerging coronaviruses.
