James Self

Dr James Self is an Associate Professor at the University of Southampton with a focus on improving clinical outcomes for children with visual disorders. His research integrates genetics, bioinformatics, and clinical trials to address conditions like albinism, nystagmus, and amblyopia.

• PhD in Ophthalmic Molecular Genetics (MRC Clinical Research Training Fellowship)
• Higher specialist training in Paediatric Ophthalmology (Southampton, Manchester)

Research Interests span:

• Genetic eye disorders
• Neuro-ophthalmology
• Translational medicine
• Machine learning in diagnostics

Publications highlight:

• Neurodegenerative retinal pathology in mouse models
• Portable diagnostics for albinism
• Machine learning biomarkers for retinal morphology

Scientific Awards:

• Technology Advancement Award (2025)

Advising & Grants includes supervision of 5 PhD students across institutions and mentorship leading to a GW4 WELLCOME PhD award. Externally, he chairs the NIHR paediatric and neuro-ophthalmology Clinical Study Group and has held leadership roles in genomics and research ethics.