معرفی
James Moon is the J. G. Searle Professor in the Department of Pharmaceutical Sciences at the University of Michigan College of Pharmacy. His research integrates immunology, pharmaceutics, and engineering to develop novel immunotherapies and vaccines targeting cancer, autoimmune diseases, and gut microbiome disorders.
His educational background includes a B.S. in Bioengineering from UC Berkeley (2002), Ph.D. in Bioengineering from Rice University (2008), and postdoctoral training at MIT/HHMI in Materials Science & Engineering (2008-2012).
Moon's research focuses on designing nanotechnology-based drug delivery systems to modulate immune responses. His lab develops biomimetic materials including nanogels, nanoparticles, and biomimetic vesicles for oral immunotherapy, STING pathway activation, and microbiome engineering. Key applications target food allergy suppression, cancer immunotherapy, and autoimmune disease treatment through precise immune modulation.
Recent publications demonstrate a strong emphasis on metalloimmunotherapies, STING-activating nanoparticles, and gut microbiome modulation for cancer therapy. His work bridges fundamental immunology with translational applications, featuring innovative approaches like inulin-gel oral immunotherapies and manganese-based nanocarriers for enhanced antitumor immunity.
No scientific awards were mentioned in the source material.
Dr. Moon leads the Moon Lab at the University of Michigan NCRC facility (B10-A190), mentoring graduate students and postdoctoral researchers. His research program is supported by federal grants focused on developing next-generation immunotherapies through interdisciplinary collaboration with clinicians and engineers.
The Moon Lab utilizes advanced high-throughput methods and nanotechnology platforms to detect and improve immune functions, with current projects emphasizing oral delivery systems for gut-immune axis modulation and combination chemoimmunotherapies for solid tumors.
