معرفی
James Lissemore is a Professor in the Department of Biology at John Carroll University, where he conducts research on germline stem cell regulation using C. elegans as a model organism. His work bridges molecular genetics and developmental biology to understand fundamental stem cell mechanisms.
Education:
- B.A. in Microbiology from Rutgers University
- Ph.D. in Molecular Biology from the University of Wisconsin, Madison
- Post-doctoral research in cloning and regulation of glycolytic enzyme genes in D. melanogaster at Syracuse University
- Post-doctoral research in genetic and molecular analysis of germline development in C. elegans at Syracuse University
Dr. Lissemore's research centers on the genetic control of germline stem cell self-renewal and differentiation, with particular focus on Notch signaling pathways and molecular chaperones like HSP90. His laboratory employs C. elegans to dissect conserved mechanisms of stem cell regulation, investigating how genes such as glp-1 and ekl-1 maintain germline integrity through precise control of cell fate decisions. This work has significant implications for understanding stem cell biology across species.
Analysis of his publication record reveals sustained contributions to molecular genetics spanning four decades, with recent work emphasizing C. elegans germline development and historical research covering phytochrome gene regulation and Drosophila glycolytic enzymes. His articles consistently employ molecular techniques like PCR and genetic screening to explore gene function in model organisms.
At John Carroll University, Dr. Lissemore teaches core biology courses including Principles of Biology, Genetics, Molecular Genetics, and Biotechnology Lab. He maintains an active research laboratory in the Dolan Science Center (room W241) where his team investigates germline stem cell regulation through genetic and molecular approaches.
