James Grotberg

James Grotberg, Ph.D., M.D., is a Professor in the Department of Biomedical Engineering at the University of Michigan. His research focuses on biofluid mechanics with emphasis on respiratory and cardiovascular systems. He leads the Biofluid Mechanics Research Laboratory, investigating topics such as lung airway dynamics in diseases like asthma and emphysema, surfactant/drug delivery in cystic fibrosis and neonatal care, and two-phase flow effects in lung tissue damage. His work combines experimental and computational approaches, collaborating with clinical researchers. Key research areas include artificial organs, biofluids, biomechanics, and tissue engineering.

Dr. Grotberg’s research spans computational pulmonary edema modeling, airway closure mechanisms (including elastoviscoplastic mucus properties), and microfluidic lung models for disease simulation. His recent work addresses liquid plug rupture dynamics, peristaltic flow in glymphatic systems, and surfactant delivery optimization. He has developed computational models for acute respiratory distress syndrome (ARDS) and artificial implantable lungs/placentas. His research integrates fluid dynamics principles with biological systems to advance medical therapies and diagnostics.

He holds a primary appointment in the College of Engineering and collaborates with clinical and engineering departments. His research has been published in leading journals, focusing on fluid-structure interactions in biological systems. No specific awards or grants are listed in the provided text.