Jaehyuk Choi

Jaehyuk Choi, MD, PhD is an Adjunct Professor in the Department of Dermatology at Northwestern University Feinberg School of Medicine, with additional affiliation in Biochemistry and Molecular Genetics. His work bridges clinical dermatology with cutting-edge research in skin cancer and immunology, focusing on translating molecular discoveries into improved diagnostic and therapeutic approaches for patients.

Education:

• BA: Harvard University (1998)
• PhD: Yale University (2006)
• MD: Yale University School of Medicine (2006)
• Resident: Yale University, Dermatology (2010)
• Postdoctoral Fellow: Yale University, Genetics (2012)

Dr. Choi's research spans three interconnected domains: computational clinical oncology and dermatology, where his team applies high-dimensional assays to evaluate disease drivers and construct personalized treatment frameworks; mechanistic dissection of skin cancer, utilizing human and mouse models to elucidate how genetic and epigenetic changes affect tumor cells and their microenvironment; and technology development, creating innovative solutions for scientific challenges that lack off-the-shelf approaches. His work particularly focuses on T-cell lymphomas, immune regulation in skin cancers, and developing novel therapeutic strategies.

Scientific Awards:

• Emerging Leader Award, Mark Foundation (2022)
• Member, American Society for Clinical Investigation (2021)
• Research Scholar, American Cancer Society (2020)
• New Innovator Award, National Institutes of Health (NIH) (2018)
• Clinical Investigator Award, Damon Runyon Cancer Research Foundation (2016)

Dr. Choi actively mentors a diverse team of students and researchers, including MD/PhD candidates, graduate students, and postdoctoral scholars. His laboratory receives funding from multiple sources including the NIH, American Cancer Society, and various foundations. He serves in leadership roles for several professional organizations and contributes to scientific advancement through editorial board positions at journals including JCI and Leukemia and Lymphoma.

The Choi Lab operates as a multidisciplinary research hub within the Robert H Lurie Medical Research Center, collaborating with several institutes including the Center for Genetic Medicine, Center for Human Immunobiology, and Simpson Querrey Institute for Epigenetics. The lab maintains active partnerships with clinical departments and research centers across Northwestern to translate basic science discoveries into patient care improvements.