معرفی
Jacques Robidoux, Ph.D., is an Assistant Professor at the Department of Pharmacology & Toxicology, East Carolina University School of Medicine. His research focuses on molecular mechanisms of adipose tissue expansion and remodeling, particularly the interplay between angiogenesis and adipogenesis in metabolic health.
- Research spans autocrine/paracrine signaling in adipocyte precursor recruitment
- Investigates vascular remodeling through sprouting angiogenesis and progenitor cell differentiation
- Examines metabolic syndrome implications of adipose tissue dysfunction
Key contributions include elucidating EGFR-IGF-1R collaboration in preadipocyte proliferation and lipogenesis, and exploring MAP kinase roles in UCP1 regulation. His work demonstrates that adipocyte number defects may drive metabolic syndrome more than total adipose mass.
Laboratory members include Research Specialist Bin Luo. Studies employ human/mouse preadipocytes, adipose explants, and genetically engineered murine models to dissect molecular pathways.
