معرفی
Jack R. Harkema is a University Distinguished Professor and holder of the Albert C. and Lois E. Dehn Endowed Chair in Veterinary Medicine at Michigan State University's College of Veterinary Medicine. He serves as Director of the Laboratory for Environmental & Toxicologic Pathology and the Mobile Air Research Laboratories (AirCARE 1 and 2). His research focuses on understanding how environmental and occupational air pollutants cause respiratory, cardiovascular, and autoimmune diseases using laboratory animal models.
- B.S. in Biology/Chemistry, Calvin College (1975)
- M.S. in Physiology, Michigan State University (1977)
- D.V.M., Michigan State University (1980)
- Postdoctoral Fellowship, Lovelace Respiratory Research Institute (1980-82)
- Residency in Veterinary Anatomic Pathology, UC Davis (1982-85)
- Ph.D. in Comparative Pathology, UC Davis (1985)
Dr. Harkema's research interests center on environmental & occupational health with emphasis on air pollution effects. He investigates cellular and molecular targets for interventions against pollutant-induced diseases, focusing on ozone, particulate matter, and silica dust. His work explores how chronic diseases affect susceptibility to environmental toxins and develops dietary interventions for autoimmune conditions.
Recent publications highlight his expertise in inhalation toxicology with studies on AHR pathway disruptions in hepatotoxicity, antiviral protein design for MERS-CoV inhibition, and autoimmune disease modulation through nutritional approaches. His article trends show strong emphasis on environmental health policy, inflammatory pathways, and translational research across toxicology and veterinary medicine.
- Career Achievement Award, Society of Toxicologic Pathology
- Val Vallyathan Award, American Thoracic Society
- Fellow of American Thoracic Society
- Board Certification, American College of Veterinary Pathologists
As an educator, Dr. Harkema teaches general pathology, comparative pathology, and respiratory pathobiology. His service roles include past membership in US EPA's Clean Air Science Advisory Committee and leadership positions in the Environmental Health Policy Committee of the American Thoracic Society. The laboratory he directs develops mobile research platforms for community-based exposure studies, including Navajo Nation collaborations.
