معرفی
Isabelle Baconguis is an Assistant Professor at the Vollum Institute, Oregon Health & Science University, with a focus on structural mechanisms of ion channels and membrane proteins. She earned a B.A. in Biochemistry from the University of Pennsylvania (2005) and a Ph.D. in Neuroscience from OHSU (2013).
- Key research tools: X-ray crystallography, electrophysiology, cryo-EM
- Research themes: Sodium channels, acid-sensing ion channels (ASICs), channel assembly/gating, structural biology of membrane proteins
Her 2025 Structure paper reveals subunit-dependent regulation in epithelial sodium channels, while earlier work (2014–2020) explores:
- Cryo-EM methods for time-resolved imaging
- Epithelial sodium channel architecture
- AMPA receptor-TARP complexes
- Toxin modulation of ion channels
Scientific Awards:
- NIH Director's Early Independence Award (2013–2018)
- Ruth L. Kirschstein NRSA Fellowship (2011–2013)
Her publications across 15+ journals span structural biology, neuroscience, and biochemistry, with high-impact work on sodium-binding sites in transporters (2007) and cross-disciplinary tools like Appia for chromatography analysis (2023).
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