معرفی
Inna Rozman Grinberg is a Senior Researcher at Stockholm University's Department of Biochemistry and Biophysics, where she has worked since 2017. She is a member of Britt-Marie Sjöberg's research group, focusing on ribonucleotide reductase (RNR) regulation and its potential as an antimicrobial target.
Her research investigates transcriptional and allosteric regulation of RNRs, essential enzymes for DNA synthesis and repair in bacteria. She discovered the NrdR regulatory protein in 2006 and continues exploring its molecular mechanisms, bacterial specificity, and drug development potential.
- 2025: Work on ATP-cone domain regulation and NrdR DNA binding
- 2024: Structural analysis of anaerobic RNRs and NrdR regulatory mechanisms
- 2022: Investigations into NrdR's transcriptional control in bacterial genomes
Recent publications highlight her expertise in:
- ATP-cone domain function
- Metal cofactor analysis in RNRs
- Structural biology using SAXS and cryo-EM
- Antimicrobial target development
She received a Carl Trygger foundation grant to host a post-doctoral fellow studying NrdR. Her work combines biochemical, biophysical, and bioinformatics approaches with structural biology collaborations.
